Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS).The latter mutations may exert toxicity by increasing FUS accumulation.We show here that broad expression within the nervous system of wild-type or either of two ALS-linked mutants of human FUS in mice produces progressive motor phenotypes accompanied by cha
Cervical cancer kicker pro comp 10 is the fourth leading cause of cancer-related death in women worldwide, with 90% of cases occurring in low- and middle-income countries (LMICs).There has been a global effort to increase access to affordable screening in these settings; however, a corresponding increase in availability of effective and inexpensive
To date, nanomaterials have been widely used for the treatment and diagnosis of rheumatoid arthritis.Amongst various nanomaterials, polymer-based nanomaterials are becoming increasingly popular in nanomedicine due to their functionalised fabrication and easy synthesis, making them biocompatible, cost-effective, biodegradable, and efficient nanocarr
The gut microbiota of amphibians is affected by exogenous and endogenous factors.We performed a comprehensive analysis using high-throughput sequencing technology and functional predictions and observed general changes in the gut microbiota of frogs in different growth stages, seasons, and growth environments.There were no significant differences i